Anthropic just built a model so dangerous, they’re not even going to release it (for now). On TWiST, Jason, Alex, and Neurometric CEO Rob May discuss whether or not this is just another frontier model or a potential weapon of mass internet destruction. Claude Mythos Preview is already in the hands of over 40 Anthropic partners — including Nvidia, Apple, Amazon, Microsoft, and Google — as part of its “Project Glasswing” security council. Together, they’ll test how quickly and easily the model can thwart today’s most elite cybersecurity protocols, and try to develop fresh protocols to keep our most sensitive and critical software systems safe and intact. Once Mythos or a similarly powerful model hits the streets… it’s all over! Plus, we’re checking out the real-time SaaSpocalypse monitor Death By Clawd, and chatting with its creator, Gyani, about how it feels to have your startup one-shotted by Anthropic’s latest model. Guests: Rob May: https://x.com/robmay Neurometric: https://www.neurometric.ai/ Neurometric SLM Marketplace: https://marketplace.neurometric.ai/ Death by Clawd: https://deathbyclawd.com/ Nick O’Neill: https://x.com/chooserich Related Links: Anthropic’s Project Glasswing: https://www.anthropic.com/glasswing Anthropic Mythos Risk Report: https://www-cdn.anthropic.com/79c2d46d997783b9d2fb3241de43218158e5f25c.pdf Polymarket Anthropic Predictions: https://polymarket.com/predictions/anthropic CyberGym: https://github.com/sunblaze-ucb/cybergym SWE-Bench: https://www.swebench.com/ Greg Brockman on Alex Kantrowitz podcast: https://www.youtube.com/watch?v=J6vYvk7R190 DARPA Cyber Grand Challenge: https://www.darpa.mil/research/programs/cyber-grand-challenge Notable Quotes "There's a really good chance that this is going on behind the scenes that we don't even know. China may have already accomplished this." — Jason Calacanis "By 2030, 90% of common work tasks will be able to be done by a 10 billion parameter model or smaller." — Rob May "Lovable built an AI that writes code for you, which is adorable — because Claude already writes code for you without the $20 per month middleman tax." — Death by Clawd This Week In Startups is made possible by: LinkedIn Jobs -https:// LinkedIn.com/twist Grasshopper Bank - https://Grasshopper.bank/twist Render - https://Render.com/twist Plaud - https://Plaud.ai/twist Today’s show: Timestamps: 0:00 Anthropic's new, powerful 'Mythos' model 3:00 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! 4:36 Neurometric's Rob May joins the show 9:14 Sam Altman's talent exodus 10:12 Render - Go to https://render.com/twist to apply for the Render Startup Program. You'll get anywhere from $500 to $100,000 in free credits. 11:00 Has Anthropic Passed OpenAI? 14:54 When will Claude release Mythos? Polymarket: https://polymarket.com/event/claude-mythos-released-by 17:42 The AI race turns existential 18:26 Would Anthropic's model give the CIA the ability to hack a foreign government? 19:29 Grasshopper Bank - Time is money. Don't waste either. Go to https://grasshopper.bank/twist and get an exclusive $500 cash bonus just for opening an account. 20:29 Should AI be nationalized? 27:43 Thomas Friedman: claims anthropic is talking with the US gov. regarding security concerns 28:53 Subsidizing secret AI development. 29:44 LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at https://LinkedIn.com/twist 30:39 How much of the military's $1.5T will go to AI cybersecurity? 34:27 Nick O'Neill's "not sponsored" call-in. 37:34 What is an SLM? 41:11 Tactical/Practical: How can you tune SLMs 44:53 How Neurometric can afford 100M free tokens per month for its users? 48:14 What is "harness engineering"? 50:08 Tactical/ Practical: Every Reddit rant is a startup idea 59:35 Why Meta is the most un-innovative AI company in the world. 1:02:53 Gyani of Deathbclawd joins the show — Is your company COOKED? Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason’s suite of newsletters: https://substack.com/@calacanis Follow TWiST: Twitter: https://twitter.com/TWiStartups YouTube: https://www.youtube.com/thisweekin Instagram: https://www.instagram.com/thisweekinstartups TikTok: https://www.tiktok.com/@thisweekinstartups Substack: https://twistartups.substack.com